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EmiliaU///U
EmiliaU///U
Aug 17, 2018
#FOR-MY-DAUGHTER-I-MIGHT-EVEN-BE-ABLE-TO-DEFEAT-THE-DEMON-KINGMhw da best
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Kyon
Kyon
Aug 17, 2018
#FOR-MY-DAUGHTER-I-MIGHT-EVEN-BE-ABLE-TO-DEFEAT-THE-DEMON-KINGWarning!!!
Cuteness Overload!!!
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ArchNightWolf
ArchNightWolf
Aug 12, 2018
#FOR-MY-DAUGHTER,-I-MIGHT-EVEN-BE-ABLE-TO-DEFEAT-THE-DEMON-KINGso cuteeeee.
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♥UwU Luna♥
♥UwU Luna♥
Aug 21, 2018
#Dungeon-Nurserythis is just like summoned demon lord to other world(¬_¬)
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MollitoWO
MollitoWO
Jun 08, 2019
Demon Slayer

Song: Gurenge
By: LISA
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Myramillan
Myramillan
Jan 24, 2025
In the blink of an eye, the procedure changed into the following: mine ores make smelt of ore to forge bronze daggers chicken execution, then sell the rest to the greedy clerk at the shop, and use the cash to buy tools. And on and so forth it goes on. As of now I've consumed all the energy drinks available I have available. I've never had to fight this intensely in my entire life to get rid of chickens. I took another bottle of red bull, knowing it could be quite a, hard night.

As a kid I didn't experience that tight loop Jagex has created with their world. Everything worked. I did not realize that the shopkeeper took away of your hard-earned chicken breasts, because before were I an ordinary account I would have traded them to another user at a price ten times greater than. Being an ironman, you must master the mechanics of each skill to build.

I had my second revelation after I became bored of the chickens and set out to develop my archery ability: "Ranged." I focused on the job to be completed, using the money I received from my shopkeeper, I purchased a bronze hatchet at the Lumbridge Axe store. I then cut down a nearby tree. wood is checked. After that, I returned at the store's general department. I believe that the storekeeper was expecting me. The shopkeeper's robe smelled of chicken from his lunch, and he smiled his evil, corrupted grin. Unwillingly, I spent the rest portion of my coins to purchase an instrument: required to flytch to my bow. Fletching and checking.

There was the bow's husk that began to form the next item to my wish list were flax from the nearby fields, and the spinning wheel so that I could construct the bowstring. Within a short time I had my own bow, and I sat on my couch for an while with a smile in my eyes. I was starting to realize the game's concept all about. There is a lot of satisfaction when you earn your living from this game. If I had played an account that was normal, the procedure could have been streamlined to purchasing the bow from the Grand Exchange and carrying on my way.

I did not realize until later that the making of a bow required use of a variety of abilities: woodcutting to make an ax, farming to harvest the flax, then fletching to make the bow, and connect the bowstring. Then came the next goal of my archery instruction and ammunition. Then my practice changed into mines for minerals, making smiths for the making of arrowheads and then fletching to make the design of archers. Even my blood feud with the chickens paid off when they produced feathers to make my archers.

Within the first couple of hours, my perspective of the game shifted into more expansive. The game's mechanics in the Ironman mode appear to be targeted towards experienced players who have a long time ago finished their end-game content and are looking for new challenges. This is not to say that the game aren't played and loved by everyone both old and new. I must take my bow to Jagex for this The mechanic operates in ways I didn't comprehend until I experienced it.
Rsorder.com: The most professional site to Buy OSRS Gold/RS3 Gold, items, accounts, power leveling, and questing services.
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Myramillan
Myramillan
Jan 19, 2025
In the blink of an eye, the procedure changed into the following: mine ores make smelt of ore to forge bronze daggers chicken execution, then sell the rest to the greedy clerk at the shop, and use the cash to buy tools. And on and so forth it goes on. As of now I've consumed all the energy drinks available I have available. I've never had to fight this intensely in my entire life to get rid of chickens. I took another bottle of red bull, knowing it could be quite a, hard night.

As a kid I didn't experience that tight loop Jagex has created with their world. Everything worked. I did not realize that the shopkeeper took away of your hard-earned chicken breasts, because before were I an ordinary account I would have traded them to another user at a price ten times greater than. Being an ironman, you must master the mechanics of each skill to build.

I had my second revelation after I became bored of the chickens and set out to develop my archery ability: "Ranged." I focused on the job to be completed, using the money I received from my shopkeeper, I purchased a bronze hatchet at the Lumbridge Axe store. I then cut down a nearby tree. wood is checked. After that, I returned at the store's general department. I believe that the storekeeper was expecting me. The shopkeeper's robe smelled of chicken from his lunch, and he smiled his evil, corrupted grin. Unwillingly, I spent the rest portion of my coins to purchase an instrument: required to flytch to my bow. Fletching and checking.

There was the bow's husk that began to form the next item to my wish list were flax from the nearby fields, and the spinning wheel so that I could construct the bowstring. Within a short time I had my own bow, and I sat on my couch for an while with a smile in my eyes. I was starting to realize the game's concept all about. There is a lot of satisfaction when you earn your living from this game. If I had played an account that was normal, the procedure could have been streamlined to purchasing the bow from the Grand Exchange and carrying on my way.

I did not realize until later that the making of a bow required use of a variety of abilities: woodcutting to make an ax, farming to harvest the flax, then fletching to make the bow, and connect the bowstring. Then came the next goal of my archery instruction and ammunition. Then my practice changed into mines for minerals, making smiths for the making of arrowheads and then fletching to make the design of archers. Even my blood feud with the chickens paid off when they produced feathers to make my archers.

Within the first couple of hours, my perspective of the game shifted into more expansive. The game's mechanics in the Ironman mode appear to be targeted towards experienced players who have a long time ago finished their end-game content and are looking for new challenges. This is not to say that the game aren't played and loved by everyone both old and new. I must take my bow to Jagex for this The mechanic operates in ways I didn't comprehend until I experienced it.
Rsorder.com: The most professional site to Buy OSRS Gold/RS3 Gold, items, accounts, power leveling, and questing services.
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Myramillan
Myramillan
Jan 19, 2025
In the blink of an eye, the procedure changed into the following: mine ores make smelt of ore to forge bronze daggers chicken execution, then sell the rest to the greedy clerk at the shop, and use the cash to buy tools. And on and so forth it goes on. As of now I've consumed all the energy drinks available I have available. I've never had to fight this intensely in my entire life to get rid of chickens. I took another bottle of red bull, knowing it could be quite a, hard night.

As a kid I didn't experience that tight loop Jagex has created with their world. Everything worked. I did not realize that the shopkeeper took away of your hard-earned chicken breasts, because before were I an ordinary account I would have traded them to another user at a price ten times greater than. Being an ironman, you must master the mechanics of each skill to build.

I had my second revelation after I became bored of the chickens and set out to develop my archery ability: "Ranged." I focused on the job to be completed, using the money I received from my shopkeeper, I purchased a bronze hatchet at the Lumbridge Axe store. I then cut down a nearby tree. wood is checked. After that, I returned at the store's general department. I believe that the storekeeper was expecting me. The shopkeeper's robe smelled of chicken from his lunch, and he smiled his evil, corrupted grin. Unwillingly, I spent the rest portion of my coins to purchase an instrument: required to flytch to my bow. Fletching and checking.

There was the bow's husk that began to form the next item to my wish list were flax from the nearby fields, and the spinning wheel so that I could construct the bowstring. Within a short time I had my own bow, and I sat on my couch for an while with a smile in my eyes. I was starting to realize the game's concept all about. There is a lot of satisfaction when you earn your living from this game. If I had played an account that was normal, the procedure could have been streamlined to purchasing the bow from the Grand Exchange and carrying on my way.

I did not realize until later that the making of a bow required use of a variety of abilities: woodcutting to make an ax, farming to harvest the flax, then fletching to make the bow, and connect the bowstring. Then came the next goal of my archery instruction and ammunition. Then my practice changed into mines for minerals, making smiths for the making of arrowheads and then fletching to make the design of archers. Even my blood feud with the chickens paid off when they produced feathers to make my archers.

Within the first couple of hours, my perspective of the game shifted into more expansive. The game's mechanics in the Ironman mode appear to be targeted towards experienced players who have a long time ago finished their end-game content and are looking for new challenges. This is not to say that the game aren't played and loved by everyone both old and new. I must take my bow to Jagex for this The mechanic operates in ways I didn't comprehend until I experienced it.
Rsorder.com: The most professional site to Buy OSRS Gold/RS3 Gold, items, accounts, power leveling, and questing services.
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Myramillan
Myramillan
Jan 24, 2025
In the blink of an eye, the procedure changed into the following: mine ores make smelt of ore to forge bronze daggers chicken execution, then sell the rest to the greedy clerk at the shop, and use the cash to buy tools. And on and so forth it goes on. As of now I've consumed all the energy drinks available I have available. I've never had to fight this intensely in my entire life to get rid of chickens. I took another bottle of red bull, knowing it could be quite a, hard night.

As a kid I didn't experience that tight loop Jagex has created with their world. Everything worked. I did not realize that the shopkeeper took away of your hard-earned chicken breasts, because before were I an ordinary account I would have traded them to another user at a price ten times greater than. Being an ironman, you must master the mechanics of each skill to build.

I had my second revelation after I became bored of the chickens and set out to develop my archery ability: "Ranged." I focused on the job to be completed, using the money I received from my shopkeeper, I purchased a bronze hatchet at the Lumbridge Axe store. I then cut down a nearby tree. wood is checked. After that, I returned at the store's general department. I believe that the storekeeper was expecting me. The shopkeeper's robe smelled of chicken from his lunch, and he smiled his evil, corrupted grin. Unwillingly, I spent the rest portion of my coins to purchase an instrument: required to flytch to my bow. Fletching and checking.

There was the bow's husk that began to form the next item to my wish list were flax from the nearby fields, and the spinning wheel so that I could construct the bowstring. Within a short time I had my own bow, and I sat on my couch for an while with a smile in my eyes. I was starting to realize the game's concept all about. There is a lot of satisfaction when you earn your living from this game. If I had played an account that was normal, the procedure could have been streamlined to purchasing the bow from the Grand Exchange and carrying on my way.

I did not realize until later that the making of a bow required use of a variety of abilities: woodcutting to make an ax, farming to harvest the flax, then fletching to make the bow, and connect the bowstring. Then came the next goal of my archery instruction and ammunition. Then my practice changed into mines for minerals, making smiths for the making of arrowheads and then fletching to make the design of archers. Even my blood feud with the chickens paid off when they produced feathers to make my archers.

Within the first couple of hours, my perspective of the game shifted into more expansive. The game's mechanics in the Ironman mode appear to be targeted towards experienced players who have a long time ago finished their end-game content and are looking for new challenges. This is not to say that the game aren't played and loved by everyone both old and new. I must take my bow to Jagex for this The mechanic operates in ways I didn't comprehend until I experienced it.
Rsorder.com: The most professional site to Buy OSRS Gold/RS3 Gold, items, accounts, power leveling, and questing services.
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Brian Ott III
Brian Ott III
Aug 15, 2018
#Lord-Xue-Yingthis is great i love it.

P.S I hate the blood witch she is such a b**ch
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Tokyo_Shimura
Tokyo_Shimura
May 25, 2020
Jesus Christ know i realized that puppet is a male possessed by a female and then by a bear .-,
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AkiraMrqz
AkiraMrqz
Aug 19, 2018
#BJ-Alexoh my lord esto se esta poniendo fuerte
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Val-sama
Val-sama
Aug 20, 2018
#Tensei-Shitara-Slime-Datta-Ken-The-Ways-of-Strolling-in-the-Demon-Countryis cool, but i prefer the original
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Mr. Yuri Inspector
Mr. Yuri Inspector
Sep 30, 2019
Kimetsu no Yaiba (Demon slayer)

Y’all probably know this anime by now, but for anyone who hasn’t yet watched it,

Demon Slayer is one of the best anime that has came out in 2019, and this is because of its insanely good visuals,
NESUKOOOOO, sublime sound tracks and effects and NESUKOOOOO
There isn’t anything that original in the story, but it doesn’t have to be. Because they implement the same story so magnificently that you just can’t stop watching it.
Also, it has cliffhangers (Which don’t matter right now but THEY WERE SO FRICKING ROUGH LIKE UGH WHY WOULD YOU NOT LEAVE US LIKE THAT UFOTABLE)

The characters are loveable characters that don’t stop being interesting and you ultimately become fond with all of them.

I don’t want to give almost any spoilers, because this is an anime that you really should watch, you would definitely regret not watching it.


In conclusion, nezuko is precious and she is the best girl in the anime universe without a doubt.
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NyaSyka
NyaSyka
Feb 09, 2021
The demon guy ... Looks very cute ❤️
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Ichigo Kurosaki
Ichigo Kurosaki
Aug 21, 2018
#WataShu-Why-Can-t-I-Stop-Being-the-Heroine-Xd
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Ridham
Ridham
May 02, 2025
Targeted drug delivery system Market Growth and Status Explored in a New Research Report 2035
The prevalence of chronic diseases has increased significantly over the past few decades. Presently, around 129 million people in the US have at least one life threating chronic condition, such as heart disease, cancer, diabetes, obesity or hypertension.

The global targeted drug delivery device market size is projected to grow from $427 Million in 2026 to $2,153 Million by 2035, representing a CAGR of 19.7% during the forecast period.

Additionally, about 90% of the annual USD 4.1 trillion health care expenditure is attributed to managing and treating chronic diseases and mental health conditions. Thus, rising incidence of chronic diseases, coupled with aging population has led to a surge in the demand for novel drugs, including complex small molecules and biologics, across multiple therapeutic areas.

The pharmaceutical industry is increasingly shifting towards biologics over traditional small molecule drugs due to their higher specificity and efficacy in treating complex diseases, particularly through targeted drug delivery devices. Biologics are designed to interact with specific cellular targets, which can lead to more effective treatments with fewer side effects. In 2023, the US FDA approved around 20 biologics for various indications, highlighting their growing acceptance. However, the administration of biologics often requires injections rather than oral routes, posing challenges for patient compliance. Further, over the years, biologics have demonstrated a high success rate (more than 70%) in various clinical trials across different therapeutic areas. As the industry continues to innovate, enhancing drug delivery systems will be crucial for maximizing the benefits of biologics.

Advantages of targeted drug delivery device
Targeted Drug Delivery Devices offer a number of benefits. Some of the key advantages offered by these devices are summarized below:

 Minimally Invasive: Current systems for delivering cell therapies are often inefficient and require invasive procedures for direct injection into targeted tissues. For patients with conditions like heart failure, multiple invasive surgeries are required to achieve optimal therapeutic effects due to the need for several injections. In contrast, targeted drug delivery devices offer a solution by enabling localized therapies to be administered minimally invasively as many times as required. These devices are implanted into the target tissue through a single surgical procedure, after which the cells within the device's reservoir can produce therapeutic effects and facilitate the healing of damaged tissue. Additionally, catheter-based injection systems have been shown to effectively provide safe and minimally invasive targeted delivery of cell therapies.
 Limited Systemic Toxic Side-effects: Majority of the biologics, including cell therapies, gene therapies and immunotherapies are being delivered systemically rather than being delivered directly to the targeted site. The systemic administration of these therapies can cause toxicity by activating the immune response, resulting in adverse side effects such as fatigue, nausea, easy bruising, and infection. Additionally, patients often need to visit clinics every week or two for frequent repeated administrations of these therapies. The targeted drug delivery devices deliver the therapeutics to the targeted site easily, maximizing target site exposure, generate elicit efficient therapeutic response, and reduces the risk of immunogenicity.
 Sustained Delivery: The high tumoral pressure makes it challenging for a drug to be effective when administered directly to the tumor in a single dose. This is primarily due to the fact that only a small amount of drug gets reaches the targeted site while the remaining gets eliminated. The intra-tumoral implantable drug delivery devices represent a significant advancement in the field of cancer therapy by enabling sustained drug release. These systems are designed to release therapeutic agents at a controlled rate, significantly improving treatment efficacy and safety.
 Encapsulated Cell Therapy Implants: Targeted drug delivery via encapsulated cell therapy implants enables the safe and efficient administration of cell therapies. Encapsulation of therapeutic cells and their implantation into the surgical cavity allows for long term release of active compounds at the required site, reducing side effects associated with systemic delivery. Most encapsulation strategies also function as biomimetic scaffolds, providing the necessary structural support for cell survival and proliferation.

Research objectives:
• The Targeted Drug Delivery Device Market report studies the worldwide market consumption rate in terms of value and volume.
• It identifies the various sub-segments of the market structure.
• It proffers information regarding the leading global manufacturers in this industry, describing their market value & share, sales volume, competitive analysis, SWOT analysis, and development strategies adopted during the forecast timeline.
• The report describes the key industry players, with respect to their individual growth trends, future prospects, and contribution to the global market, and explains the factors related to their market growth potential, drivers, opportunities, threats, and industry-specific challenges.
• Furthermore, the report underpins the strategic developments occurring in the global market, such as expansions, mergers & acquisitions, agreements, as well as new product launches.

Thank you for reading our report. Kindly get in touch with us to know more about the report or to receive a customized copy of it. Our team will ensure the report is tailored according to your needs.
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Rayshawn Andrade
Rayshawn Andrade
Jul 29, 2021
my anime drawings please leave comments and likes . i rayshawn am a very big fan of anime 30 years old and very tired of being single I'm looking for a nice beautiful single girlfriend. my cell phone number is( 786) 397 -1264
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Elise Elleneth
Elise Elleneth
Jan 16, 2019
Later, am going to update the novel ESCORT... I have to edit first and polish my English. ☺
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nanalie
nanalie
Aug 24, 2018
#BOKU-NO-NEESANfirst! now that I think about it what the heck am I doing i should be preparing lunch by now instead of reading
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